Does Drinking Coffee Help Counteract the Harms of a Sedentary Lifestyle?
BACKGROUND AND PURPOSE:
- Zhou et al. (BMC Public Health, 2024) evaluated the independent and joint associations of daily sitting time and coffee intakes with mortality from all-cause and cardiovascular disease (CVD) among US adults
METHODS:
- Prospective cohort study
- National Health and Nutrition Examination Survey (NHANES) Survey
- 2007 to 2018
- Participants
- US adults
- Exposures
- Daily sitting time
- Coffee consumption per 24-hour period
- Study design
- Adjusted hazard ratio (HR) calculated using Cox proportional hazards regression
- Primary outcomes
- All-cause mortality
- CVD mortality
RESULTS:
- 10,639 participants
- Deaths 945 | Deaths from CVD: 284
- Compared to those who sat <4 h/d, sitting more than 8 h/d was associated with higher risks of mortality
- All-cause mortality: HR 1.46 (95% CI, 1.17 to 1.81)
- CVD mortality: HR 1.79 (95% CI, 1.21 to 2.66)
- Compared with non-coffee drinkers, people in the highest quartile of coffee consumption had reduced risks of mortality
- All-cause: HR 0.67 (95% CI, 0.54 to 0.84)
- CVD mortality: HR 0.46 (95% CI, 0.30 to 0.69)
- Compared to coffee drinkers who sat for <6h/d, sedentary non-coffee drinkers had a higher risk of all-cause mortality while sedentary coffee drinkers did not
- Sedentary non-coffee drinkers: HR 1.58 (95% CI, 1.25 to 1.99)
- Sedentary coffee drinkers: HR 1.22 (95% CI, 0.97 to 1.54)
CONCLUSION:
- Risk of all-cause and CVD mortality is higher among individuals leading a sedentary lifestyle, but risk was reduced among coffee drinkers
- The authors state
Notably, the results of a joint analysis of this study identified that that the association of sedentary with increased mortality was only observed among adults with no coffee consumption but not among those who had coffee intake
Given that coffee is a complex compound, further research is needed to explore this miracle compound
